The Role of Polyunsaturated Fatty Acids and Moringa Oleifera Leaf in Primary Osteoporosis Induced by Insomnia: Pathophysiological Mechanisms and Agricultural Implications

Abstract

Moringa oleifera leaves are rich in polyunsaturated fatty acids (PUFAs), which may help geriatric bone health in a balanced diet. These leaves are anti-inflammatory and calcium-enhancing due to their magnesium, vitamin C, vitamin A, and calcium content. Omega-6 polyunsaturated fatty acids may exceed osteoporosis risk. Moringa may improve sleep quality for osteoporosis patients using omega-6 fatty acid-reducing medication. This study examines whether polyunsaturated fatty acid consumption in elderly Chinese adults increases the risk of primary osteoporosis and sleep problems. Insomnia is linked to primary osteoporosis in this population. In the cross-sectional investigation, 400 people over 60 participated. Sleep duration, polyunsaturated fatty acid consumption, and bone mineral density were measured using standardised questionnaires. Evidence from logistic regression analysis links PUFA intake to a higher risk of early-onset osteoporosis (odds ratio = 2.796; p < 0.05). Conversely, increased PUFA intake and shorter sleep duration reduced osteoporosis risk (odds ratio = 0.406, p = 0.05). Omega-3 polyunsaturated fatty acids may reduce sleep deprivation's negative effects, according to research. These findings add to the evidence that polyunsaturated fatty acids (PUFAs) benefit bone health. However, high polyunsaturated fatty acid intake may raise osteoporosis risk. Adding Moringa oleifera leaves and PUFAs to the diet may help older persons maintain bone density. Moringa may mitigate omega-6 polyunsaturated fatty acid effects by boosting calcium and reducing inflammation. Moringa leaves are rich in calcium, magnesium, vitamins A and C. Along with complete treatment, lowering omega-6 fatty acid consumption may help osteoporosis patients with sleeplessness. Moringa has anti-inflammatory benefits, however some people react negatively. These findings suggest that public health campaigns should promote healthy eating in older persons. Including polyunsaturated fats with Moringa oleifera leaves in diets may be beneficial. Educational efforts should emphasise the benefits of moringa in an omega-3 fatty acid-rich diet for sleep, bone health, and polyunsaturated fatty acid reduction.