Formulation, Characterization, and Microbial Studies of Herbal Remedy for Asthma Patients

Abstract

Asthma is a lung inflammatory disease present all over the world. Environmental conditions and genetic factors play a critical role in the progress and management of this disease. In Pakistan, the air pollution index increases rapidly especially smog intensify the severity of asthma.  Patients use corticosteroids to overcome asthma allergens that cause negative effects on the body.  Keeping in view the present investigation is based on herbal remedies i.e., herbal infusion tea, formulated from a natural source. These are made from herbs such as black seed, lemongrass, viola, ginger, and cardamom. The main bioactive compound in the herbal infusion tea was thymoquinone. There were three different formulations (F1, F2, and F3) made. Chemical analysis, water activity, pH, detection of thymoquinone, microbiological studies, and sensory evaluation were performed. The bioactive compound was detected by a fourier transform infrared analyzer at 1636.05 and 2340.87 and microbiological studies show that after the infusion of tea in boiled water, all forms of microbes were removed and safe for drinking. F3 formulation was the best formulation selected based on the sensory evaluation that contains moisture 8.50%±0.32, ash 8.30%±0.82, cured fiber 26.35%±1.30, crude fat 8.20%±0.35, total solid 91.50%±0.82, water activity0.60±0.03 and pH 5.33±0.04. This study was conducted on 10 patients, 7 out of 10 given positive responses and feel batter in their health. Herbal infusion teas are the most effective product for asthma patients and store a long period of time. Herbal formulation has the ability to cope with asthma allergens and does not cause side effects on the body.